Due to the COVID-19 pandemic, the 2021 Adelaide International has been moved to Melbourne as part of the ATP's updated start to the season calendar and will be called the Murray River Open. Staged on the eve of the Australian Open, the ATP 250 tournament debuted in Adelaide under the brand-new Memorial Drive Tennis Centre roof in 2020. Russia's Andrey Rublev won the inaugural edition - his first of a tour-best five titles that season.